Abstract and Applied Analysis
Volume 2008 (2008), Article ID 239870, 19 pages
doi:10.1155/2008/239870

An existence result to a strongly coupled degenerated system arising in tumor modeling

L. Hadjadj1 , K. Hamdache2 and D. Hamroun3

1Faculté des Sciences, Université de Blida, BP 270, Blida 09000, Algeria
2Ecole Polytechnique, CMAP, CNRS, 91128 Palaiseau Cedex, France
3Faculté de Mathématiques, Université des Sciences et de la Technologie Houari Boumediene, BP 32 El Alia, Alger 16111, Algeria

Abstract

We consider a mathematical model to describe the growth of a vascular tumor including tumor cells, macrophages, and blood vessels. The resulting system of equations is reduced to a strongly 2×2 coupled nonlinear parabolic system of degenerate type. Assuming the initial data are far enough from 0, we prove existence of a global weak solution with finite entropy to the problem by using an approximation procedure and a time discrete scheme.